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Randomized clinical trials comparing antibiotic therapy with appendicectomy for uncomplicated acute appendicitis: meta-analysis.

26 January 2023
Randomized clinical trials Colorectal
Herrod PJJ, Kwok AT, Lobo DN.

BJS Open 2022; 6: zrac100.

Eight RCTs including 3203 participants were analyzed. Early optimism about the benefits of antibiotic therapy were tempered in this analysis by reduced treatment efficacy compared with appendicectomy, higher readmission rate, and no advantage in duration of stay at index admission.

Comment: Antibiotic treatment for appendicitis has a place, but not as standard therapy.

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rct140
Randomized clinical trials
Randomized clinical trials
Colorectal
Randomized clinical trials comparing antibiotic therapy with appendicectomy for uncomplicated acute appendicitis: meta-analysis.
Herrod PJJ, Kwok AT, Lobo DN.
26012023
BJS Open 2022; 6: zrac100.
Eight RCTs including 3203 participants were analyzed. Early optimism about the benefits of antibiotic therapy were tempered in this analysis by reduced treatment efficacy compared with appendicectomy, higher readmission rate, and no advantage in duration of stay at index admission.
Comment: Antibiotic treatment for appendicitis has a place, but not as standard therapy.
Published on: 26 January 2023
Article ID: rct140

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