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BJS Academy
The BJS Academy is the educational arm of the BJS Foundation. A hub to meet, learn, be mentored, discuss, listen and understand the education and accreditation opportunities available
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The BJS Foundation owns complementary surgical publications, BJS and BJS Open, renowned for the exceptional quality of their peer review and editorial processes.
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The BJS Foundation is a charitable body with a mission to advance and improve education in surgery and to diffuse knowledge on new and improved methods of teaching and practicing surgery in all branches.
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Randomized clinical trials

The randomized clinical trials section is produced following a review of the content of the best surgical journals published in English worldwide. The section editor is Jonothan Earnshaw, former director of the BJS Academy and Consultant Vascular Surgeon at Gloucestershire Hospitals NHS Foundation Trust, UK, in conjunction with editor assistant Jenny Moon.

RCT of the Month

Hospital policy of tranexamic acid to reduce transfusion in major noncardiac surgery

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27 August 2026

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Randomized clinical trials

Hospital policy of tranexamic acid to reduce transfusion in major noncardiac surgery

Transanal irrigation for low anterior resection syndrome treatment: international multicentre randomized clinical trial

Cost-effectiveness of the gluteal turnover flap for perineal wound closure after abdominoperineal resection: randomized clinical trial.

Collagen implant versus gluteus maximus flap for perineal closure after extended abdominoperineal excision: NEAPE randomized clinical trial

Negative-pressure wound therapy in thoracic and abdominal surgery: meta-analysis of randomized trials

Perioperative serplulimab with neoadjuvant chemotherapy versus perioperative chemotherapy in PD-L1-positive gastric cancer (ASTRUM-006): a randomized, double-blind, multicentre, phase 3 study

Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 10-year efficacy and late normal tissue effects from a multicentre, open-label, non-inferiority, phase 3, randomized controlled trial and 5-year efficacy results from a randomized axillary substudy

Interventions to reduce postoperative mortality in low-and middle-income countries: a systematic review

Prevention of parastomal hernia with funnel-shaped intra-abdominal mesh versus no mesh for rectal adenocarcinoma surgery: 3-year follow-up of a randomized clinical trial

Robot-assisted versus conventional minimally invasive oesophagectomy for oesophageal squamous cell carcinoma (RAMIE): a multicentre, open-label, randomized, phase 3, non-inferiority trial

Cryoanalgesia increases neuropathic pain in adults undergoing minimally invasive surgery: a 1-year follow-up of a randomized study

Early enteral versus oral postoperative nutrition after pancreatoduodenectomy: the NUTRIWHI randomized clinical trial

Effect of noise isolation during general anaesthesia on the incidence of moderate-to-severe pain after major abdominal surgery: multicentre randomized clinical study

Endovascular therapy for post-thrombotic syndrome - a randomized trial

Economic evaluation of lymphaticovenous anastomosis versus conservative therapy for breast cancer-related lymphoedema: secondary outcome analysis of a randomized clinical trial

Small bites versus large bites for closure of abdominal midline incisions: a randomized clinical trial

Segment 4b/5 versus wedge resection for gallbladder adenocarcinoma: a randomized controlled trial

Neoadjuvant chemotherapy versus upfront surgery in patients with locally advanced colon cancer: a randomized clinical trial

Preliminary results of open excisional hemorrhoidectomy combined with 3% polidocanol foam sclerotherapy in patients with IV-degree hemorrhoidal disease: a randomized controlled open-label single-center study

Transanal total mesorectal excision versus laparoscopic total mesorectal excision for mid and low rectal cancer (COLOR III): short-term outcomes of an international, multicentre, phase 3, randomised, controlled, non-inferiority trial

The ILEOSTIM trial: A multicentre randomised controlled trial evaluating the impact of efferent loop stimulation prior to ileostomy reversal on postoperative ileus

Preoperative low-energy diets for patients with a body mass index> 30 kg/m2 undergoing non-bariatric surgery: pilot feasibility randomized clinical trial and a systematic review and meta-analysis of efficacy data

Indocyanine green fluorescence angiography for anastomotic perfusion assessment in colorectal surgery: a systematic review with meta-analysis, meta-regression, and trial sequential analyses

Long-term outcomes after laparoscopic versus open adhesiolysis for small bowel obstruction: The LASSO randomized clinical trial

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