Join BJS Academy
BJS Academy>Randomized clinical ...>Pyridostigmine to re...
Normal View Dyslexic View

Pyridostigmine to reduce the duration of postoperative Ileus after colorectal surgery (PyRICo-RCT): randomized clinical trial.

7 August 2024
Randomized clinical trials Colorectal
Traeger L, Bedrikovetski S, Fitzsimmons T, Nguyen T-M, Moore JW, Lewis M et al.

Br J Surg 2024; 111: znae121.

Pyridostigmine 60mg given orally twice daily after surgery reduced the duration of ileus by one day, measured by the GI-2 tool (P=0.015) in this study that included 130 patients, but did not affect the duration of hospital stay.

Comment: Apart from speeding return of bowel function, it is not clear what the benefit is overall.

BJS Foundation Limited
BJS Academy
0000-0000
BJS Foundation Limited
London, UK
rct277
Randomized clinical trials
Randomized clinical trials
Colorectal
Pyridostigmine to reduce the duration of postoperative Ileus after colorectal surgery (PyRICo-RCT): randomized clinical trial.
Traeger L, Bedrikovetski S, Fitzsimmons T, Nguyen T-M, Moore JW, Lewis M et al.
07082024
Br J Surg 2024; 111: znae121.
Pyridostigmine 60mg given orally twice daily after surgery reduced the duration of ileus by one day, measured by the GI-2 tool (P=0.015) in this study that included 130 patients, but did not affect the duration of hospital stay.
Comment: Apart from speeding return of bowel function, it is not clear what the benefit is overall.
Published on: 7 August 2024
Article ID: rct277

Related articles

Morbidity after mechanical bowel preparation and oral antibiotics prior to rectal resection. The MOBILE2 randomized clinical trial.

Koskenvuo L, Lunkka P, Varpe P, Hyoty M, Satokari R, Haapamaki C et al.

25 September 2024

Sacral neuromodulation versus conservative treatment for refractory idiopathic slow-transit constipation. The randomized clinical No.2-Trial.

Heemskerk SC, Dirksen CD, van Kuijk SMJ, Benninga MA, Baeten C, Masclee AAM et al.

30 August 2024

Impact of small-bite (5 mm) fascial closure on the incidence of incisional hernia following open colorectal cancer surgery: randomized clinical trial

Ozcan C, Colak T, Turkmenoglu O, Berkesoglu M, Ertas E.

18 September 2024
Home
  • Normal view
  • Dyslexic view
Info
Copied!