Long-term cost-effectiveness of insertion of a biological mesh during stoma-site closure: 5–8-year follow-up of the ROCSS randomized controlled trial

Reinforcement of Closure of Stoma Site (ROCSS) Collaborative and West Midlands Research Collaborative.

Br J Surg 2024; 111: znae159.

Some 598 of the original 790 patients were available for analysis. Patients who had mesh had fewer stoma site complications in the first three years, and fewer reinterventions (incidence rate ratio 0.55, 95 per cent confidence interval 0.31 to 0.97, P=0.04), but overall cost effectiveness rates were similar.

Comment: Complex trial; no overall advantage for the expensive mesh, but most complications occurred in the first three years after surgery.