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Cost-effectiveness of rubber band ligation versus hemorrhoidectomy for the treatment of grade III hemorrhoids: analysis using evidence from the HOLLAND randomized controlled trial

11 December 2025
Colorectal
BJSA
BJS Academy
0000-0000
BJS Foundation Limited
London, UK
van Oostendorp JY, Dekker L, van Dieren S, Veldkamp R, Bemelman WA, Han-Geurts IJM et al, for the HOLLAND study group.
Dis Colon Rectum 2025; 68: 1100-1111.
In this study of 79 adults, haemorrhoidectomy resulted in improved quality-adjusted life years (difference 0.08; 95 per cent confidence interval 0.04 to 0.13) and lower recurrence rates (difference 33.5%, 15.3–51.7 per cent). Hospital and societal costs were higher for haemorrhoidectomy: the incremental cost-effectiveness ratio was €24,042 per quality-adjusted life year gained and €5,918 per recurrence avoided.
Comment: Costly, but potentially durable outcomes following haemorrhoidectomy, although small sample size tempers conclusions.
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