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Appendicectomy plus standard medical therapy versus standard medical therapy alone for maintenance of remission in ulcerative colitis (ACCURE): a pragmatic, open-label, international, randomised trial

12 December 2025
Colorectal
BJSA
BJS Academy
0000-0000
BJS Foundation Limited
London, UK
The ACCURE Study Group.
Lancet Gastrohepatol 2025; 10: 550-561.
Some 301 patients were included and randomized 2:1 to appendicectomy or control groups. There were two serious adverse events after surgery. Appendicectomy reduced the colitis relapse rate over the following twelve months: 36 versus 56 per cent of patients, P=0.005.
Comment: Still controversial – is it worth it?
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