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Laparoscopic vs open distal gastrectomy for locally advanced gastric cancer. Five-year outcomes from the CLASS-01 randomized clinical trial. JAMA Surg 2022; 157: 9-17.

Huang C, Liu H, Hu Y, Sun Y, Su X, Cau H et al, for the Chinese Laparoscopic Gastrointestinal Surgery Study (CLASS) Group.
JAMA Surg 2022; 157: 9-17.

The analysis included 1039 patients from multiple centres. Overall survival rates were 72.6 per cent after laparoscopic, and 76.3 per cent after open surgery (P=0.19).

Comment; No oncological disadvantage for the laparoscopic approach.

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