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Nonoperative vs operative management of uncomplicated acute appendicitis. A systematic review and meta-analysis.

17 November 2022
Randomized clinical trials Lower GI
Leite RMA, Seo DJ, Gomez-Eslava B, Hossain S, Lesegretain A, de Souza AV et al.

JAMA Surg. ;157: 828-834.

This analysis of eight RCTs showed that the main outcomes were similar: successful treatment at 30 days, major adverse events. The non-operative group had a longer hospital stay and a higher rate of recurrent appendicitis (18 per cent).

Comment: Useful data to help clinicians use an individualised approach.

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