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Sixty-day mortality of patients with metastatic colorectal cancer randomized to systemic treatment vs primary tumor resection followed by systemic treatment. The CAIRO4 phase 3 randomized clinical trial.
1 January 2022
Randomized clinical trials Lower GI
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This analysis of eight RCTs showed that the main outcomes were similar: successful treatment at 30 days, major adverse events. The non-operative group had a longer hospital stay and a higher rate of recurrent appendicitis (18 per cent).
Comment: Useful data to help clinicians use an individualised approach.
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