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Collagen implant versus gluteus maximus flap for perineal closure after extended abdominoperineal excision: NEAPE randomized clinical trial

27 August 2026
Colorectal
BJSA
BJS Academy
0000-0000
BJS Foundation Limited
London, UK
Rutegård M, Svensson J, Rutegård J, Rautio T, Nilsson PJ, Sjöström O et al.
BJS Open 10: zrag079.
Some 83 patients were randomized. At 6 months, 71 per cent of patients in the collagen implant group and 60 per cent in the gluteus maximus flap group underperformed the timed-stand test. Non-inferiority of the collagen implant was not demonstrated.
Comment: Functional outcomes favored the gluteus maximus flap, although findings remain exploratory.
Comment by Jeongyoon (Jenny) Moon, MD
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