Short-term outcomes of Early versus conventional adjuvant chemotherapy in stage III colon cancer: randomized clinical trial.
Lee KH, Park SY, Song SH, Kim HJ, Kim JG, Kang BW et al.
BJS Open 2023; 7: zrad064.
This study included 443 patients. Toxicity rates were similar in those randomized to early chemotherapy two weeks after surgery compared to standard intervention.
Comment: Starting chemotherapy over eight weeks after surgery is detrimental. This study suggests there is no harm (and may be benefit) in starting it two weeks after surgery.
18 October 2023Read paper
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