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Long-term outcomes of exercise therapy versus revascularization in patients with intermittent claudication.

23 November 2023
Randomized clinical trials Vascular
Shirasu T, Takagi H, Yasuhara J, Kuno T, Kent KC, Farivar BS et al. 

Ann Surg 2023; 278: 172-178.

The analysis included nine RCTs with 1477 patients. After a mean of 3.6 years of follow-up, the rate of development of critical ischaemia was similar: rate ratio 0.77, 95 per cent confidence interval 0.36 to 1.69, P=0.51. Rates of amputation and death were also similar.

Comment: No advantage to life or limb from revascularisation, but may of course benefit symptoms in the shorter term.

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