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Ten-year outcomes of a randomized clinical trial of endothermal ablation versus conventional surgery for great saphenous varicose veins
18 September 2024
Randomized clinical trials Vascular
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Terlouw LG, van Dijk LJD, van Noord D, Bakker OJ, Bijdevaate DC, Erler NS
Lancet Gastrohepatol 2024; 9: 299-309.
Ninety-four patients with chronic mesenteric ischaemia were included. Only one patient died. After 24 months, the patency of covered stents was better than bare metal stents: 81 versus 49 per cent, P<0.0001. Access site adverse events were more common in covered stent procedures.
Comment: This study does not address whether symptoms were improved alongside patency.
Effect of anticoagulant therapy for 6 weeks vs 3 months on recurrence and bleeding events in patients younger than 21 years of age with provoked venous thromboembolism. The Kids-DOTT randomized clinical trial.
JAMA 2022; 327: 129-137.
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Comment: Very low recurrence rates, but six weeks of anticoagulation seems reasonable.
Extended-course antibiotic prophylaxis in lower limb amputation: randomized clinical trial.
Souroullas P, Barnes R, Carradice D, Smith G, Huang C, Chetter I.
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In this study that included 152 procedures, the five day course reduced the rate of surgical site infection (11.8 versus 39.5 per cent, P<0.001) and revisional surgery (6.6 versus 21 per cent, P=0.01).
Comment: Is this now the standard of care?
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