Extended-course antibiotic prophylaxis in lower limb amputation: randomized clinical trial.
Souroullas P, Barnes R, Carradice D, Smith G, Huang C, Chetter I.
Br J Surg 2022; 109: 426-432.
In this study that included 152 procedures, the five day course reduced the rate of surgical site infection (11.8 versus 39.5 per cent, P<0.001) and revisional surgery (6.6 versus 21 per cent, P=0.01).
Comment: Is this now the standard of care?
2 May 2022Read paper
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