Effect of prucalopride to improve time to gut function recovery following elective colorectal surgery: randomized clinical trial.
Milne T, Liu C, O’Grady G, Woodfield J, Bissett I.
Br J Surg 2022; 109: 704–710.
Return of gut function was not improved by prucalopride, a serotonin agonist, 2 mg given before surgery and 2 mg daily for six days, in this study that included 148 patients.
Comment: Disappointing.
19 September 2022
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