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Effect of Denonvilliers’ fascia preservation versus resection during laparoscopic total mesorectal excision on postoperative urogenital function of male rectal cancer patients. Initial results of Chinese PUF-01 randomized clinical trial.


Wei B, Zheng Z, Fang J, Xiao J, Han F, Huang M et al.
Ann Surg 2021; 274: e473-e480.

Some 253 men undergoing surgery for rectal cancer were included. Fascial preservation improved both the rate of urinary dysfunction (6.8 versus 25.4 per cent, P=0.003) and erectile dysfunction 12.5 versus 34.2 per cent, P=0.023).

Comment: But will it affect cancer outcomes in the longer term?

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