Adrenalectomy improves body weight, glucose, and blood pressure control in patients with mild autonomous cortisol secretion. Results of a randomized controlled trial by the Co-work Of Adrenal Research (COAR) Study.
Koh J-M, Song K, Kwak MK, Suh S, Kim B-J, Sung T-Y et al.
Ann Surg 2024; 279: 945-952.
This study included 132 patients with an asymptomatic incidental adrenaloma, but raised serum cortisol. Adrenalectomy improved weight control and diabetes control (both P=0.002) compared with the control group.
Comment: Good evidence upon which to base treatment in these patients.
30 August 2024
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