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Role of Lugol solution before total thyroidectomy for Graves’ disease: randomized clinical trial

18 September 2024
Randomized clinical trials Endocrine
Schiavone D, Crimì F, Cabrelle G, Pennelli G, Sacchi D, Mian C et al.

Br J Surg 2024; 111: znae196.

In this study that included 56 patients, preoperative use of Lugol’s significantly reduced T3 and T4 levels, but had no effect on clinical outcomes, including blood loss (80.5 versus 94ml with no Lugols’s) and duration of surgery.

Comment: Is the trial large enough to wave goodbye to Lugol’s?

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rct260
Randomized clinical trials
Randomized clinical trials
Endocrine
Role of Lugol solution before total thyroidectomy for Graves’ disease: randomized clinical trial
Schiavone D, Crimì F, Cabrelle G, Pennelli G, Sacchi D, Mian C et al.
18092024
Br J Surg 2024; 111: znae196.
In this study that included 56 patients, preoperative use of Lugol’s significantly reduced T3 and T4 levels, but had no effect on clinical outcomes, including blood loss (80.5 versus 94ml with no Lugols’s) and duration of surgery.
Comment: Is the trial large enough to wave goodbye to Lugol’s?
Published on: 18 September 2024
Article ID: rct260

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