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Lymphatic venous anastomosis and complex decongestive therapy for lymphoedema: randomized clinical trial.


Mihara M, Hara H, Kawasaki Y, Mitsuhashi T, Orikasa H, Ando H et al.

Br J Surg 2024; 111: znad372.

A total of 336 patients were included from two studies. Lymphovenous anastomosis did not reduce limb circumference or pain, but it did reduce the frequency of lymphoedema-associated cellulitis over six months, by 35 per cent in the large dataset, and by 60 per cent (95 per cent confidence interval -0.94 to -0.27 per cent) in the per protocol analysis.

Comment: The role of lymphovenous anastomosis still not clear, with only few studies outside Japan.

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