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Goal-directed perioperative albumin substitution versus standard of care to reduce postoperative complications. A randomized clinical trial (SuperAdd Trial).

27 June 2024
Randomized clinical trials General
Schaller S, Fuest K, Ulm B, Schmid S, Bubb C, Eckstein H-H et al.

Ann Surg 2024; 279: 402-409.

Some 2509 patients having high-risk, non-cardiac surgery with low serum albumin postoperatively were randomized to albumin substitution or treatment only in an emergency. Complication rates were unaffected by the albumin treatment: 84.7 versus 87.3 Percent in controls.

Comment: Another attempt to support albumin treatment in the acute situation fails. It remains unclear why.

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rct002
Randomized clinical trials
Randomized clinical trials
General
Goal-directed perioperative albumin substitution versus standard of care to reduce postoperative complications. A randomized clinical trial (SuperAdd Trial).
Schaller S, Fuest K, Ulm B, Schmid S, Bubb C, Eckstein H-H et al.
27062024
Ann Surg 2024; 279: 402-409.
Some 2509 patients having high-risk, non-cardiac surgery with low serum albumin postoperatively were randomized to albumin substitution or treatment only in an emergency. Complication rates were unaffected by the albumin treatment: 84.7 versus 87.3 Percent in controls.
Comment: Another attempt to support albumin treatment in the acute situation fails. It remains unclear why.
Published on: 27 June 2024
Article ID: rct002

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