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Five-year survival outcomes of laparoscopy-assisted vs open distal gastrectomy for advanced gastric cancer. The JLSSG0901 Randomized Clinical Trial.

19 July 2023
Randomized clinical trials Upper GI
Etoh T, Ohyama T, Sakaramoto S, Tsuji T, Lee S-W. Yoshida K et al,  for the Japanese Laparoscopic Surgery Study Group (JLSSG).

JAMA Surg 2023; 158: 445-454.

After five years in this study that included 502 patients, there was no difference between the two procedures in relapse-free survival: 73.9 per cent open versus 75.5 per cent laparoscopic resection, P=0.03 for non inferiority. Nor were there differences in postoperative complications, or overall survival.

Comment: No difference in outcomes, so choice of procedure should be according to patient choice, but perhaps also cost in publicly funded healthcare systems.

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