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Effect of laparoscopic and open pancreaticoduodenectomy for pancreatic or periampullary tumors. Three-year follow-up of a randomized clinical trial.

Qin T, Zhang H, Pan S, Liu J, Li D, Chen R et al, for the Minimally Invasive Treatment Group in the Pancreatic Disease Branch of China’s International Exchange and Promotion Association for Medicine and Healthcare (MITG-P-CPAM).

Ann Surg 2024; 279: 605-612. 

This multicentre study from China included 656 procedures. 3-year overall survival was 59.1 per cent after laparoscopic  surgery for malignant disease versus 54.3 per cent after open surgery (P=0.33).

Comment: Big study confirming long term survival after laparoscopic surgery no worse than after open surgery.

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