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Effect of a home-based, walking exercise behavior change intervention vs usual care on walking in adults with peripheral artery disease. The MOSAIC randomized clinical trial.

2 May 2022
Randomized clinical trials Vascular
Bearne M, Volkmer B, Sekhon M, Fisher G, Galea Homes MN, Douiri A, et al for the MOSAIC Trial Collaboration.

JAMA 2022; 327: 1344-1355.

The study included 190 participants randomly allocated to a walking exercise behaviour change intervention by physiotherapists. After three months, those who had received the intervention had an improved 6-minute walking test by around 30m (P=0.009).

Comment: The questions remain whether this improvement is meaningful and durable.

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