This website uses cookies to improve your experience.

Cookie policy

Dual antiplatelet treatment up to 72 Hours after ischemic stroke

Gao Y, Chen W, Pan Y, Jing J, Wang C, Johnston SC et al, for the INSPIRES investigators

N Engl J Med 2023; 389:2413-2424.

Some 6100 patients were included; most were randomized over 24h after the new event. A new stroke within 90 days occurred in 7.3 percent of the dual antiplatelet group compared with 9.2 per cent of those given aspirin alone (hazard ratio 0.79, 95 per cent confidence interval 0.66 to 0.94; P=0.008).

Comment: Although small increase in risk of bleeding, a conclusive result due to the large number of participants, and contemporary data.

Read paper


Part of the charitable activity of the Foundation, BJS Academy is an online educational resource for current and future surgeons.

The Academy is comprised of five distinct sections: Continuing surgical education, Young BJS, Cutting edge, Scientific surgery and Surgical news. Although the majority of this is open access, additional content is available to BJS subscribers and strategic partners.

Discover the Academy
Surgeon Training & Surgeons in Surgery