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Povidone iodine vs chlorhexidine gluconate in alcohol for preoperative skin antisepsis. A randomized clinical trial.

Widmer AF, Atkinson A, Kuster P, Wolfensberger A, Klimke S, Sommerstein R et al.
BJSA
BJS Academy
0000-0000
BJS Foundation Limited
London, UK
JAMA 2024; 332: 541-549.
Some 3360 patients having cardiac and abdominal surgery were randomized to one of two alcoholic antiseptic solutions for skin cleansing. Surgical site infection rates were similar after povidone iodine (5.1 per cent) and chlorhexidine (5.5 per cent).
Comment: Is the alcohol more important than the antiseptic?

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