Join BJS Academy
BJS Academy>Randomized clinical ...>Hypothermia or machi...
Normal View Dyslexic View

Hypothermia or machine perfusion in kidney donors.

22 March 2023
Randomized clinical trials Transplantation
Malinoski D, Saunders S, Swain S, Groat T, Wood PR, Reese J et al.

N Engl J Med 2023; 388: 418-426.

Some 1349 kidneys were transplanted from 725 deceased donors. Hypothermia was inferior to machine perfusion (or both) in terms of delayed graft function (30 versus 19 per cent), but after one year, graft survival rates were similar.

Comment: So the question is whether reduced delayed graft function is sufficient justification for machine perfusion.

BJS Foundation Limited
BJS Academy
0000-0000
BJS Foundation Limited
London, UK
rct130
Randomized clinical trials
Randomized clinical trials
Transplantation
Hypothermia or machine perfusion in kidney donors.
Malinoski D, Saunders S, Swain S, Groat T, Wood PR, Reese J et al.
22032023
N Engl J Med 2023; 388: 418-426.
Some 1349 kidneys were transplanted from 725 deceased donors. Hypothermia was inferior to machine perfusion (or both) in terms of delayed graft function (30 versus 19 per cent), but after one year, graft survival rates were similar.
Comment: So the question is whether reduced delayed graft function is sufficient justification for machine perfusion.
Published on: 22 March 2023
Article ID: rct130

Related articles

Ex vivo kidney machine perfusion: meta-analysis of randomized clinical trials

Kang M, Kim S, Choi JY, Kim KS, Jung YK, Park B et al. 

20 May 2024

Temporary portocaval shunt provides superior intraoperative hemodynamics and reduces blood loss and duration of surgery in live donor liver transplantation. A randomized controlled trial.

Kumar M, Patil NS, Mohapatra N, Sindwani G, Dhingra U, Yadav A et al.
Ann Surg 2024; 279: 932-944.

16 August 2024

Impact of portable normothermic blood-based machine perfusion on outcomes of liver transplant. The OCS Liver PROTECT randomized clinical trial.

Markmann JF, Aboulijoud MS, Ghobrial RM, Bhati CS, Pelletier SJ, Lu AD et al.

2 May 2022
Home
  • Normal view
  • Dyslexic view
Info
Copied!