Author response: Enhancing methodological rigour in prepectoral breast reconstruction studies

Correspondence to: Raafat Gendy (email: raafat.gendy1@nhs.net)

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Correspondence to: Janhavi Venkataraman (email: Janhavi.Venkakataraman@hcahealthcare.co.uk; janhavivraman@gmail.com)

The London Breast Institute

Princess Grace Hospital

Breast cancer is the most common cancer affecting women worldwide. It is likely that many people reading this know someone who has been affected by this condition. For many, surgery remains the cornerstone of curative treatment. Breast cancer surgery has advanced significantly since the first radical mastectomies of the late 19th century to today’s refined breast-conserving and reconstructive techniques.

Surgery remains a key component of treatment of breast cancer. For early-stage disease, removing the tumour can be enough to eradicate cancer completely. In more advanced cases, surgery is complemented by chemotherapy, radiotherapy, and hormone therapy.

The success of breast cancer surgery has not happened by chance. It reflects decades of rigorous research, often led by surgeons. Trials that once compared radical mastectomy with breast-conserving surgery laid the foundations for a global shift in practice. Randomised studies in axillary surgery demonstrated that less can be more, avoiding major complications such as lymphoedema without compromising oncological standards. The surgical research forces driving this rapid development have changed lives. They also act as an exemplar for other specialties.