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Assessment of laparoscopic spleen-preserving hilar lymphadenectomy for advanced proximal gastric cancer without invasion into the greater curvature. A randomized clinical trial.

Lin J-X, Lin J-P, Wang Z_K, Li P, Xie J-W, Wang J-B et al.

JAMA Surg 2023; 158: 10-18.

In this study that included 526 patients with proximal gastric cancer that had not invaded the greater curvature, the studied procedure did not improve 3-year disease-free survival compared to standard gastrectomy: 70.3 vs. 64.3 per cent, respectively, P=0.11).

Comment: Subgroup analysis suggested that patients with advanced posterior gastric cancer may benefit from this procedure.

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