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Antibiotics versus placebo in adults with CT-confirmed uncomplicated acute appendicitis (APPAC III): randomized double-blind superiority trial.

13 July 2022
Randomized clinical trials Upper GI
Salminen P, Sippola S, Haijanen J, Nordström P, Rantanen T, Rautio T et al. 

Br J Surg 2022: 109: 503-509.

Seventy-two patients with CT confirmed uncomplicated appendicitis for non operative treatment were included.  The ten day successful treatment rate was 87 per cent with placebo and 97 per cent with antibiotics, (P=n.s)

Comment: So how would a surgeon  today choose to be treated if they had uncomplicated appendicitis?

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rct212
Randomized clinical trials
Randomized clinical trials
Upper GI
Antibiotics versus placebo in adults with CT-confirmed uncomplicated acute appendicitis (APPAC III): randomized double-blind superiority trial.
Salminen P, Sippola S, Haijanen J, Nordström P, Rantanen T, Rautio T et al. 
13072022
Br J Surg 2022: 109: 503-509.
Seventy-two patients with CT confirmed uncomplicated appendicitis for non operative treatment were included.  The ten day successful treatment rate was 87 per cent with placebo and 97 per cent with antibiotics, (P=n.s)
Comment: So how would a surgeon  today choose to be treated if they had uncomplicated appendicitis?
Published on: 13 July 2022
Article ID: rct212

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