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Antibiotics versus placebo in adults with CT-confirmed uncomplicated acute appendicitis (APPAC III): randomized double-blind superiority trial.

Salminen P, Sippola S, Haijanen J, Nordström P, Rantanen T, Rautio T et al. 

Br J Surg 2022: 109: 503-509.

Seventy-two patients with CT confirmed uncomplicated appendicitis for non operative treatment were included.  The ten day successful treatment rate was 87 per cent with placebo and 97 per cent with antibiotics, (P=n.s)

Comment: So how would a surgeon  today choose to be treated if they had uncomplicated appendicitis?

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