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Ultrasound-assisted carbon nanoparticle suspension mapping versus dual tracer-guided sentinel lymph node biopsy in patients with early breast cancer (ultraCars): phase III randomized clinical trial.

Zhang L, Cheng M, Lin Y, Zhang J, Shen B, Chen Y et al.

Br J Surg 2022; 109: 1232–1238.

In this study that included 330 women, the sentinel node identification rate was similar: 94.5 per cent with ultrasound assistance versus 95.8 per cent with dual tracer. Number of sentinel nodes, number of metastatic nodes and duration of surgery were similar between the groups.

Comment: Ultrasound-assisted carbon nanoparticle mapping was non inferior.

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