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The efficacy of liposomal bupivacaine on postoperative pain following abdominal wall reconstruction. A randomized, double-blind, placebo-controlled trial.


Fafaj A, Krpata D, Petro CC, Prabhu AS, Rosenblatt S, Tastaldi L et al.

Ann Surg 2022; 276: 224-232.

In this three-way study that included 164 procedures, opioid requirement at 72h was similar with and without local anaesthesia.

Comment: A transversus abdominis block was inadequate to affect analgesia requirement after this surgery.

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