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Preoperative dexamethasone administration in hepatectomy of 25-min intermittent Pringle’s maneuver for hepatocellular carcinoma: a randomized controlled trial.

13 February 2024
Randomized clinical trials HPB
Huang Y, Xu L, Wang N, Wei Y, Wang W, Xu M et al.

Int J Surg 2023 109: 3354-3364.

Some 277 procedures were included. Perioperative use of dexamethasone 10mg, improved postoperative biochemical liver function and reduced major complications (14.1. vs. 24.2 per cent, P= 0.031) and postoperative hospital stay (median 6 vs 7 days, P=0.046).

Comment: Simple medication with potentially significant effect.

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