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Laparoscopic versus open hemihepatectomy: The ORANGE II PLUS multicenter randomized controlled trial.

27 June 2024
Randomized clinical trials HPB
Fichtinger RS, Aldrighetti LA, Hilal MA, Troisi RI, Sutcliffe RP, Besselink MG et al, for the ORANGE II PLUS Collaborative.

J Clin Oncol 2024; 42: 1799-1809.

In this study of 332 procedures, patients who had the laparoscopic approach had improved functional recovery (4 vs 5 days, P<0.001), and were able to access neoadjuvant treatment earlier: 46.5 versus 62.8 days, P=0.009).

Comment: Perhaps most importantly patients who had laparoscopic surgery were able to have their chemotherapy earlier.

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