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Laparoscopic versus open hemihepatectomy: The ORANGE II PLUS multicenter randomized controlled trial.


Fichtinger RS, Aldrighetti LA, Hilal MA, Troisi RI, Sutcliffe RP, Besselink MG et al, for the ORANGE II PLUS Collaborative.

J Clin Oncol 2024; 42: 1799-1809.

In this study of 332 procedures, patients who had the laparoscopic approach had improved functional recovery (4 vs 5 days, P<0.001), and were able to access neoadjuvant treatment earlier: 46.5 versus 62.8 days, P=0.009).

Comment: Perhaps most importantly patients who had laparoscopic surgery were able to have their chemotherapy earlier.

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