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Endoscopic sleeve gastroplasty for treatment of class 1 and 2 obesity (MERIT): a prospective, multicentre, randomised trial.

26 October 2022
Randomized clinical trials Upper GI
Dayyeh PKA, Bazerbachi F, Vargas EJ, Sharaiha RZ, Thompson CC, Thaemert BC et al, for the MERIT Study Group.

Lancet 2022; 400: 441-451.

After one year, mean percentage excess weight loss was 49.2 per cent after sleeve gastrectomy compared to 3.2 per cent in controls, P<0.0001, in this study that included 209 patients. There were only three serious adverse events (2 per cent) after surgery.

Comment: Strong evidence for benefit from sleeve gastrectomy in the short term.

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