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Endoscopic sleeve gastroplasty for treatment of class 1 and 2 obesity (MERIT): a prospective, multicentre, randomised trial.


Dayyeh PKA, Bazerbachi F, Vargas EJ, Sharaiha RZ, Thompson CC, Thaemert BC et al, for the MERIT Study Group.

Lancet 2022; 400: 441-451.

After one year, mean percentage excess weight loss was 49.2 per cent after sleeve gastrectomy compared to 3.2 per cent in controls, P<0.0001, in this study that included 209 patients. There were only three serious adverse events (2 per cent) after surgery.

Comment: Strong evidence for benefit from sleeve gastrectomy in the short term.

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