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Effect of adjuvant steroid therapy in type 3 biliary atresia. A single-center, open-label, randomized controlled trial.

29 August 2023
Randomized clinical trials HPB
Lu X, Jiang J, Shen Z, Chen G, NP YW, Xiao X et al.

Ann Surg 2023; 277: e1200-e1207.

A total of 200 babies with Kasai disease were randomly allocated adjuvant steroids after portoenterostomy. After six months, the proportion of babies who were jaundice-free and had avoided liver transplantation was higher in those treated with steroids: 54.1 versus 31 per cent, P=0.0015.

Comment: Should become routine care.

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rct095
Randomized clinical trials
Randomized clinical trials
HPB
Effect of adjuvant steroid therapy in type 3 biliary atresia. A single-center, open-label, randomized controlled trial.
Lu X, Jiang J, Shen Z, Chen G, NP YW, Xiao X et al.
29082023
Ann Surg 2023; 277: e1200-e1207.
A total of 200 babies with Kasai disease were randomly allocated adjuvant steroids after portoenterostomy. After six months, the proportion of babies who were jaundice-free and had avoided liver transplantation was higher in those treated with steroids: 54.1 versus 31 per cent, P=0.0015.
Comment: Should become routine care.
Published on: 29 August 2023
Article ID: rct095

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