Kinoshita J, Hayashi S, Tsuji T, Moriyama H, Yamazaki Y, Kitano Y et al.
BJS Open 2026; 10: zrag031.
Some 140 patients were included, and patients receiving intravenous acetaminophen had comparable pain scores when compared to thoracic epidural analgesia (risk difference -4.1 per cent; 95 per cent confidence interval -24.3 to 16.6). Secondary outcomes including rescue analgesic use, patient satisfaction, and recovery were comparable.
Comment: Scheduled IV acetaminophen was non-inferior to epidural analgesia, challenging the need for routine epidural use after minimally invasive gastrectomy.
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