Padillo-Ruiz J, Fresno C, Suarez G, Blanco G, Muñoz-Bellvis L, Justo I et al.
BJS Open 2024;
8: zrae123.
In this study that included 101 procedures, median metastasis-free survival was similar: 12.4 months in the SMA group and 18.1 months in the no-touch group; P=0.73. Circulating tumour cells measured during the procedure predicted earlier distant metastases, and was less common in the no-touch group.
Comment: Complicated trial, and interesting work concerning tumour cell measurement intra-operatively. Larger numbers of procedures need to be studied for clear differences.
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