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Antibiotic prophylaxis for acute cholecystectomy: PEANUTS II multicentre randomized non-inferiority clinical trial.

1 March 2022
Randomized clinical trials HPB
Van Braak WG, Ponten JEH, Loozen CS, Schots JPM, van Geloven AAW, Donkervoort SC et al.
Br J Surg 2022 109: 267-273.

Some 226 patients with mild to moderate cholecystitis were included. Use of antibiotics reduced the rate of all infections (7.1 versus 12.6 per cent), and in particular surgical site infections (5.3 versus 12.1 percent; P=0.01).

Comment: Antibiotics recommended.

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rct230
Randomized clinical trials
Randomized clinical trials
HPB
Antibiotic prophylaxis for acute cholecystectomy: PEANUTS II multicentre randomized non-inferiority clinical trial.
Van Braak WG, Ponten JEH, Loozen CS, Schots JPM, van Geloven AAW, Donkervoort SC et al.Br J Surg 2022 109: 267-273.
01032022
Some 226 patients with mild to moderate cholecystitis were included. Use of antibiotics reduced the rate of all infections (7.1 versus 12.6 per cent), and in particular surgical site infections (5.3 versus 12.1 percent; P=0.01).
Comment: Antibiotics recommended.
Published on: 1 March 2022
Article ID: rct230

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