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Adjustable intragastric balloon for treatment of obesity: a multicentre, open-label, randomised clinical trial.

Barham KAD, Maselli DB, Rapaka B, Lavin T, Noar M, Hussan H et al.
Lancet 2021; 398: 1965-1973.

This multicentre study included 288 patients randomized to lifestyle intervention with additional intragastric balloon therapy. After 32 weeks, mean total bodyweight loss was greater in the balloon group: 15 versus 3.3 per cent (P,0.0001). Some 17 per cent of balloons were removed for intolerance.

Comment: This is now an old technology that has never really taken off.

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