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The conventional technique versus the no-touch isolation technique for primary tumor resection in patients with colon cancer (JCOG1006). A multicenter, open-label, randomized, phase III trial.


Takii Y, Mizusawa J, Kanemitsu Y, Komori K, Shiozawa M, Ohue M et al.

Ann Surg 2022; 275: 849-855.

Use of the no touch technique during colon cancer resection failed to improve three year disease-free survival in this multicentre study that included 853 procedures: hazard ratio 1.03, 95 per cent confidence interval 0.8 to 1.3, P=0.59.

Comment: Perhaps other factors are just more important.

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