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Short postoperative intravenous versus oral antibacterial therapy in complicated acute appendicitis. A pilot noninferiority randomized trial.


Lipping E, Sten S, Reinsoo A, Artjom B, √úlle K, Lepner U et al.

Ann Surg 2024; 279: 191-195.

Some 104 patients who had surgery for complicated appendicitis were randomly allocated intravenous or oral antibiotics for 24h. Complication rates were non-inferior for oral antibiotics.

Comment: Good to avoid intravenous antibiotics.

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