Efficacy and safety of intraoperative hyperthermic intraperitoneal chemotherapy for locally advanced colon cancer. A phase 3 randomized clinical trial.
Arjona-Sánchez A, Espinosa-Redondo E, Gutiérrez-Calvo A, Segura-SampedroJJ, Pérez-Viejo E, Concepción-Martin V et all for the Grupo Español de Carcinomatosis Peritoneal.
JAMA Surg 2023; 158: 683-691.
A total of 184 patients underwent cytoreductive surgery with or without HIPEC. The three year locoregional control rate was improved by additional HIPEC: 97.6 versus 87.6 per cent, P=0.03. Disease-free survival was similar between the groups. Patients with stage pT4 disease were particularly advantaged.
Comment: Data to help identify those who will benefit most.
12 October 2023Read paper
Part of the charitable activity of the Society, BJS Academy is an online educational resource for current and future surgeons.
The Academy is comprised of five distinct sections: Continuing surgical education, Young BJS, Cutting edge, Scientific surgery and Surgical news. Although the majority of this is open access, additional content is available to BJS subscribers and strategic partners.