Effect of interval between neoadjuvant chemoradiotherapy and surgery on disease recurrence and survival in rectal cancer: long-term results of a randomized clinical trial.
Akgun E, Caliskan C, Bozbiyik O, Yoldas T, Doganavasargil B, Ozkok S et al.
BJS Open 2022; 6: zrac107.
Although locoregional recurrence was higher at five years (10.1 per cent if over 8 weeks after chemotherapy versus 6.9 per cent if less than 8 weeks, P=0.14), disease-free and overall survival were similar in this study that included 350 patients.
Comment: Remains controversial, but no clear evidence here that waiting for surgery is detrimental.
21 December 2022
Read paperAcademy
Part of the charitable activity of the Society, BJS Academy is an online educational resource for current and future surgeons.
The Academy is comprised of five distinct sections: Continuing surgical education, Young BJS, Cutting edge, Scientific surgery and Surgical news. Although the majority of this is open access, additional content is available to BJS subscribers and strategic partners.
