Prophylactic central neck lymph node dissection in low-risk thyroid carcinoma patients does not decrease the incidence of locoregional recurrence. A meta-analysis of randomized trials.

Sanabria A, Betancourt-Agüero C, Sánchez-Delgado J, García-Lozano C.

Ann Surg 2022; 276: 66-73.

There were five RCTs with 763 treated patients. Rates of recurrence were similar: 2.7 per cent after additional node dissection and 2.5 per cent after thyroidectomy alone. Node dissection increased the rate of permanent hypoparathyroidism: risk difference 3 per cent.

Comment; This result seems definitive.

6 September 2022

Randomized clinical trials Endocrine

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Prophylactic central neck lymph node dissection in low-risk thyroid carcinoma patients does not decrease the incidence of locoregional recurrence. A meta-analysis of randomized trials.

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