Does the use of probe-based near-infrared autofluorescence parathyroid detection benefit parathyroidectomy? A randomized single-center clinical trial.

Ann Surg 2023; 278: 549-558.

In this study that included 160 procedures, use of the probe improved the parathyroid detection rate by an experienced surgeon (3.6 versus 3.2 per procedure, P<0.001), and reduced the number of frozen section procedures required (17 versus 47, P=0.005). Detection rates were better for trainees than experienced surgeons.

Comment: Useful, but is it generalizable?