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Extracranial-intracranial bypass and risk of stroke and death in patients with symptomatic artery occlusion. The CMOSS randomized clinical trial.

23 November 2023
Randomized clinical trials Vascular
Ma Y, Wang T, Wang H, Amin-Hanjani S, Tong X, Wang J et al, for the CMOSS Investigators.

JAMA 2023; 330: 704-714.

Some 330 patients with transient ischaemic attack or non-disabling stroke were included. The endpoint was a composite of death within 30 days or ipsilateral stroke up to two years. The outcomes were similar after surgery and medical treatment: 8.6 versus 12.3 per cent respectively, P=0.39.

Comment: Still no definitive role for this procedure.

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rct068
Randomized clinical trials
Randomized clinical trials
Vascular
Extracranial-intracranial bypass and risk of stroke and death in patients with symptomatic artery occlusion. The CMOSS randomized clinical trial.
Ma Y, Wang T, Wang H, Amin-Hanjani S, Tong X, Wang J et al, for the CMOSS Investigators.
23112023
JAMA 2023; 330: 704-714.
Some 330 patients with transient ischaemic attack or non-disabling stroke were included. The endpoint was a composite of death within 30 days or ipsilateral stroke up to two years. The outcomes were similar after surgery and medical treatment: 8.6 versus 12.3 per cent respectively, P=0.39.
Comment: Still no definitive role for this procedure.
Published on: 23 November 2023
Article ID: rct068

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