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Drug-eluting resorbable scaffold versus angioplasty for infrapopliteal artery disease.

3 May 2024
Randomized clinical trials Vascular
Varcoe RL, DeRubertis BG, Kolluri R, Krishnan P, Metzger DC, Bonaca MP et al, for the LIFE-BTK Investigators.

N Engl J Med 2024;390: 9-19. 

Some 261 patients with critical ischaemia and tibial artery disease were included. The chance of avoiding amputation, vessel occlusion or further revascularisation was higher with the scaffold: 74 vs. 44 per cent, absolute difference 30 per cent, P<0.001. Serious adverse event rates were similar. 

Comment: Important study justifying the use of the drug eluting scaffold in the tibial arteries.

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rct020
Randomized clinical trials
Randomized clinical trials
Vascular
Drug-eluting resorbable scaffold versus angioplasty for infrapopliteal artery disease.
Varcoe RL, DeRubertis BG, Kolluri R, Krishnan P, Metzger DC, Bonaca MP et al, for the LIFE-BTK Investigators.
03052024
N Engl J Med 2024;390: 9-19. 
Some 261 patients with critical ischaemia and tibial artery disease were included. The chance of avoiding amputation, vessel occlusion or further revascularisation was higher with the scaffold: 74 vs. 44 per cent, absolute difference 30 per cent, P<0.001. Serious adverse event rates were similar. 
Comment: Important study justifying the use of the drug eluting scaffold in the tibial arteries.
Published on: 3 May 2024
Article ID: rct020

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