Upfront endoscopic necrosectomy or step-up endoscopic approach for infected necrotising pancreatitis (DESTIN): a single-blinded, multicentre, randomised trial.
Bang JY, Lakhtakia S, Thakkar S, Buxbaum JL, Waxman I, Sutton B et al, on behalf of the United States Pancreatic Disease Study Group.
Lancet Gastrohepatol 2024; 9: 22-33.
Seventy patients were included. Upfront necrosectomy resulted in fewer reinterventions (median 1 vs 2, P=0.003), but did not reduce mortality (none versus 2, respectively, P=0.22), or adverse events.
Comment: Smallish study, but indications of advantage for earlier intervention, rather than wait and see.
16 August 2024
Read paperAcademy
Part of the charitable activity of the Foundation, BJS Academy is an online educational resource for current and future surgeons.
The Academy is comprised of five distinct sections: Continuing surgical education, Young BJS, Cutting edge, Scientific surgery and Surgical news. Although the majority of this is open access, additional content is available to BJS subscribers and strategic partners.
