Sentinel lymph node biopsy versus axillary lymph node dissection in breast cancer patients undergoing mastectomy with one to two metastatic sentinel lymph nodes: sub-analysis of the SINODAR-ONE multicentre randomized clinical trial and reopening of enrolment
Tinterri C, Canavese G, Gatzemeier W, Barbieri E, Bottini A, Sagona A et al, for the SINODAR-ONE Collaborative Group.
Br J Surg 2023; 110: 1143-1152.
After a median of 33 months, there were five recurrence is in each group, none in the axilla. Five-year recurrence-free, and overall survival rates were also similar. It was decided to continue enrolment into the study.
Comment: An important study, but low outcome rates threaten its power, so the authors have taken the unusual (but sensible) step of reopening it.
18 October 2023
Read paperAcademy
Part of the charitable activity of the Foundation, BJS Academy is an online educational resource for current and future surgeons.
The Academy is comprised of five distinct sections: Continuing surgical education, Young BJS, Cutting edge, Scientific surgery and Surgical news. Although the majority of this is open access, additional content is available to BJS subscribers and strategic partners.
