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Hypothermia or machine perfusion in kidney donors.

Malinoski D, Saunders S, Swain S, Groat T, Wood PR, Reese J et al.

N Engl J Med 2023; 388: 418-426.

Some 1349 kidneys were transplanted from 725 deceased donors. Hypothermia was inferior to machine perfusion (or both) in terms of delayed graft function (30 versus 19 per cent), but after one year, graft survival rates were similar.

Comment: So the question is whether reduced delayed graft function is sufficient justification for machine perfusion.

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